Senior Postdoctoral Scientist – Autoantibodies
Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford
Oxford, England, United Kingdom
General Description
The Ludwig Institute for Cancer Research at the University of Oxford invites applications for a Senior Postdoctoral Scientist specializing in Autoantibodies. The successful candidate will contribute to a high-impact project involving large-scale, systematic profiling of autoantibodies across cohorts including non-cancer controls, precancerous conditions, and operable and metastatic cancers before and after immunotherapy treatments. Experimental approaches include yeast and phage display, protein arrays, cloning of autoantibodies from human peripheral blood mononuclear cells (PBMCs), and functional assessment using molecular and cellular biology techniques, including live cell imaging. Further analyses will be conducted in 2D/3D ex vivo models, organoids, and in vivo systems.
The role includes developing research questions, conducting individual research, managing academic and administrative activities, adapting and developing experimental protocols, analyzing scientific data, contributing to project strategy, delegating tasks within the research team, and mentoring junior staff. The post also involves collaboration with partner institutions, fundraising, grant applications, peer-reviewed publications, conference presentations, and public engagement.
Eligibility Criteria
- PhD in cancer biology or immunology with post-qualification research experience.
- Proven track record of contributing to supervision of students or junior staff.
- Demonstrated ability to manage research projects, collaborate effectively, and communicate scientific findings clearly.
Required expertise/skills
- Technical expertise in molecular and cellular biology, including antibody cloning and protein production/purification.
- Strong knowledge of cancer biology and/or immunology, with expertise in B cell biology, antibody production, and delivery.
- Experience with ex vivo and in vivo experimental models.
- Strong publication record with peer-reviewed first-author publications and familiarity with current literature in the field.
Salary details
Research Grade 8: £49,119 – £58,265 per annum, with a discretionary range up to £65,336 per annum. This includes a pensionable Oxford University weighting of £1,730 per year.
Application Deadline
12:00 midday on Monday, 23 April 2026