Post Doctoral Research Associate – Molecular Grammar of a Cell‑Type Specific Alternative Splicing Regulator
University of Leicester (in collaboration with the University of Cambridge)
Location
Leicester, United Kingdom (with collaborative work involving teams at the University of Cambridge)
General Description
This BBSRC‑funded postdoctoral research position invites applications from ambitious researchers to join an interdisciplinary project exploring the molecular grammar of a cell‑type specific alternative splicing regulator. The work is situated at the intersection of molecular biology, biophysics, and structural biology, and will be carried out within the Department of Biochemistry at the University of Cambridge alongside collaborators at the University of Leicester’s College of Life Sciences. The successful candidate will contribute to uncovering fundamental mechanisms of splicing regulation, working with advanced biophysical, structural, and molecular techniques as part of a collaborative academic team. The research will involve experimental design, microscopy, protein biochemistry, RNA analysis, and data interpretation within a dynamic scientific community.
Eligibility Criteria
Candidates should hold a PhD (awarded or near completion) in Biochemistry, Chemistry, Biophysics, Molecular Biology, or a closely related discipline. Demonstrated research excellence through publications and presentations will strengthen applications.
Required Expertise, Skills
Applicants should bring hands‑on experience in areas including: molecular cloning; single‑molecule microscopy (e.g., TIRF); RNA analysis (e.g., RT‑PCR); protein expression and purification; application of fluorophore/photocrosslinking methods; biophysical assays; and computational or software tools for imaging analysis (Python experience advantageous). Strong collaborative, analytical, and communication abilities are essential to thrive in this role and contribute to multi‑institutional research goals.
Salary Details
Competitive UK research salary, typically ranging approximately between £39,906 and £46,049 per annum (Grade 7), depending on experience and funding provisions.
Application Deadline
Closing date for applications is Wednesday 4 March 2026.